BioScience Trends. 2008;2(6):250-254.

Malignant mesothelioma associated with chronic empyema with elevation of serum CYFRA19: A case report.

Kodama Y, Hoshi S, Minami M, Kiso M, Takezawa T, Arai T, To Y, Teshima S, Suzuki N

Malignant neoplasms are reported to occur with long-standing tuberculous pleuritis or chronic empyema. During the clinical course of chronic empyema, subjective symptoms such as chest pain and deterioration of dyspnea and abnormal clinical signs such as increased abnormal chest shadows have frequently been found. Though difficult, differentiating the occurrence of malignant tumors from worsening chronic inflammation is crucial. We report here a case of malignant mesothelioma associated with chronic empyema with elevation of serum CYFRA19.

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