Promoting an international consensus on frailty assessment: An urgent call to address the challenges of perioperative management in an aging population

Xia Y, Tang W

BioScience Trends. 2026; 20(2):135-138.

DOI: 10.5582/bst.2026.01020

Implementation and current status of frailty assessment in Japanese hospitals: Processes, epidemiology, and future directions

Deng Y, Karako K, Yamauchi K, Song PP

BioScience Trends. 2026; 20(2):139-148.

DOI: 10.5582/bst.2025.01392

International landscape of guidelines for perioperative frailty assessment and barriers to clinical translation

Ma YN, Karako K, Xia Y, Song PP, Hu XQ

BioScience Trends. 2026; 20(2):149-159.

DOI: 10.5582/bst.2025.01389

Characteristics and management of constitutional indocyanine green excretory defect

Wang J, Hou Z, Ji J, Hu D, Wei C, Zhang Z, Zhou Y, Wang H, Huang J

BioScience Trends. 2026; 20(2):160-177.

DOI: 10.5582/bst.2026.01032

The orchestrated network of skin photoaging: From intercellular crosstalk to molecular signaling

Li BM, Ren C, Zhang LX, Gu WJ

BioScience Trends. 2026; 20(2):178-191.

DOI: 10.5582/bst.2026.01042

The ATF5-GPER1 axis drives female protection in hepatocellular carcinoma through dual tumor-suppressive and immune-modulatory mechanisms

Xu Z, Wang H, He Q, Cui H, Wu Z, Liao R

BioScience Trends. 2026; 20(2):192-204.

DOI: 10.5582/bst.2026.01026

Comparative safety and efficacy of BIC/FTC/TAF versus DTG+3TC in antiretroviral treatment-naive patients with HIV as first-line regimens: A real-world cohort study

Sun L, Jiang Y, Isnard S, Chen J, Li Y, Wang H, Zhao F, Rao M, Jia X, Huang J, Wu J, Luo Y, Zhao D, Liu C, Li X, Routy JP, Liu J, He Y, Cen P, Lu H

BioScience Trends. 2026; 20(2):205-216.

DOI: 10.5582/bst.2025.01335

Allele-specific effects of distinct SLC26A4 variants on cochlear function and transcriptomic programs in compound heterozygous models

Li Y, Yu Y, Zhao Y, Deng L, Xie J, Gao S, Li Y, Cui Q, Wang S, Huang L

BioScience Trends. 2026; 20(2):217-234.

DOI: 10.5582/bst.2026.01058

Modeling of the hepatitis B virus life cycle and the efficacy of antivirals in human iPSC-derived hepatic organoids

Liu TB, Xu JM, Chen XN, Li JY, Ke J, Xu JS, Lu HZ, Wu F

BioScience Trends. 2026; 20(2):235-244.

DOI: 10.5582/bst.2026.01043

Biallelic inactivation of EXT1 in patient-derived iPSCs confirms the "Two-hit" hypothesis in hereditary multiple osteochondromas

Yang Y, Han Z, Li G, Li Z, Shao C, Li W, Wang J, Luan J, Cui Y, Han J

BioScience Trends. 2026; 20(2):245-253.

DOI: 10.5582/bst.2026.01046